The crossroads of North America for two centuries, St. Louis knows a thing or two about hotels. The downtown area is home to several chain hotels housed in restored landmark buildings. Stay in the historic Cupples Station neighborhood and catch a Cardinals game at Busch Stadium, check out the hip restaurant scene of the revitalized Garment District, or stroll past the redbrick townhomes of the city’s oldest neighborhood, Soulard, where the bars and clubs feature live blues and jazz seven nights a week. Take a tour of the Anheuser-Busch Brewery. And no visit to St. Louis would be complete without a pilgrimage to the Gateway Arch, on the banks of the mighty Mississippi River. It is the tallest arch in the world and a symbol of America’s westward expansion.